Oxidants and asthma

被引：124

作者：

Caramori, G ^{[1
]}

Papi, A ^{[1
]}

机构：

[1] Univ Ferrara, Res Ctr Asthma & COPD, Dept Clin & Expt Med, I-44100 Ferrara, Italy

来源：

THORAX | 2004年 / 59卷 / 02期

关键词：

D O I：

10.1136/thorax.2002.002477

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Many decades of research have produced a significant amount of data showing increased oxidative stress in asthma and indicating a potential role for oxidants in the pathogenesis of the disease, particularly during exacerbations. Putatively relevant pro-oxidative mechanisms have also been identified. Currently available asthma drugs are generally effective for the treatment of the disease, but their effects on oxidative stress have still not been completely elucidated. From the data available in the literature one can conclude that antioxidant compounds may have a potential role in the treatment of asthma, especially of asthma exacerbations. More convincing evidence from controlled clinical trials is required.

引用

页码：170 / 173

页数：4

共 48 条

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