Intermolecular Atom Transfer Radical Addition to Olefins Mediated by Oxidative Quenching of Photoredox Catalysts

被引：688

作者：

Nguyen, John D.

Tucker, Joseph W.

Konieczynska, Marlena D.

Stephenson, Corey R. J. ^{[1
]}

机构：

[1] Boston Univ, Dept Chem, Boston, MA 02215 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2011年 / 133卷 / 12期

关键词：

VISIBLE-LIGHT PHOTOCATALYSIS; C-H FUNCTIONALIZATION; TRANSFER CYCLIZATION REACTIONS; ALPHA-IODO ESTERS; ELECTRON-TRANSFER; AQUEOUS-MEDIA; CARBOAZIDATION; CYCLOADDITIONS; ALDEHYDES; ORGANOCATALYSIS;

D O I：

10.1021/ja108560e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Atom transfer radical addition of haloalkanes and alpha-halocarbonyls to olefins is efficiently performed with the photocatalyst Ir[(dF(CF3)ppy)(2)(dtbbpy)]PF6. This protocol is characterized by excellent yields, mild conditions, low catalyst loading, and broad scope. In addition, the atom transfer protocol can be used to quickly and efficiently introduce vinyl trifluoromethyl groups to olefins and access 1,1-cyclopropane diesters.

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页码：4160 / 4163

页数：4

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