Total mortality is increased in rheumatoid arthritis. A 17-year prospective study

被引:85
作者
Riise, T [1 ]
Jacobsen, BK [1 ]
Gran, JT [1 ]
Haga, HJ [1 ]
Arnesen, E [1 ]
机构
[1] Univ Tromso, Inst Clin Med, N-9037 Tromso, Norway
关键词
cancer; infection; mortality; rheumatoid arthritis; sudden death;
D O I
10.1007/PL00011191
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The purpose of this study was to determine the total and cause-specific mortality in rheumatoid arthritis (PA) patients compared to a control population in northern Norway. One hundred and eighty-seven patients with RA and 930 population controls matched for age, gender and municipality were followed until death or for a maximum of 17 years. The total mortality in Rh patients was twice that of their controls (MRR = 2.0, 95% CI = 1.6-2.5). Patients possessing serum rheumatoid factors did not have a higher relative mortality than the seronegative patients. There was no statistically significant increased mortality from cancer or cardiovascular diseases. Indications for a higher death rate in RA patients than in controls were found for infection and sudden death.
引用
收藏
页码:123 / 127
页数:5
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