Effects of AC magnetic field and carboxymethyldextran-coated magnetite nanoparticles on mice peritoneal cells

被引:56
作者
Guedes, MHA
Sadeghiani, N
Peixoto, DLG
Coelho, JP
Barbosa, LS
Azevedo, RB
Kückelhaus, S
Da Silva, MD
Morais, PC
Lacava, ZGM [1 ]
机构
[1] Univ Brasilia, Inst Ciencias Biol, Dipartimento Genet & Morfol, BR-70910900 Brasilia, DF, Brazil
[2] Univ Brasilia, Fac Med, Area Morfol, BR-70910900 Brasilia, DF, Brazil
[3] Univ Brasilia, Inst Fis, BR-70919970 Brasilia, DF, Brazil
关键词
magnetic hyperthermia; magnetic fluid; cell viability; AC magnetic field; phagocytosis; hyperthermia; carboxymethyldextran; nanoparticles; toxicity; peritoneal mouse cells;
D O I
10.1016/j.jmmm.2005.02.052
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
A portable apparatus was developed to perform magnetohyperthermia (MHT) assays. In order to investigate its efficiency on cell lysis, biological effects of the AC magnetic field exposure after carboxymethyldextran-coated magnetite-nanoparticles (CMDC) treatment were investigated. Phagocyte capacity, cell viability, and morphology data evidenced that the CMDC sample and the apparatus are useful to further investigate MHT in cancer therapy. (c) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码:283 / 286
页数:4
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