Expression of platelet-derived endothelial cell growth factor (PD-ECGF) related to angiogenesis in ovarian endometriosis

被引:27
作者
Fujimoto, J [1 ]
Sakaguchi, H [1 ]
Hirose, R [1 ]
Tamaya, T [1 ]
机构
[1] Gifu Univ, Sch Med, Dept Obstet & Gynecol, Gifu 5008705, Japan
关键词
D O I
10.1210/jc.84.1.359
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Platelet-derived endothelial cell growth factor (PD-ECGF) is expressed in the lining epithelial cells of ovarian endometriomas, and in interstitial cells of the subepithelial area with angiogenesis. The expression of PD-ECGF persists in endometriotic endometrium during the menstrual cycle. This might suggest that PD-ECGF contributes to the growth of ovarian endometriomas via subepithelial angiogenesis independently of the sex steroidal milieu.
引用
收藏
页码:359 / 362
页数:4
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