A microfluidic conjugated-polymer sensor chip

被引:34
作者
Eo, Soo-Han [1 ]
Song, Simon [1 ]
Yoon, Bora [2 ]
Kim, Jong-Man [2 ]
机构
[1] Hanyang Univ, Dept Mech Engn, Seoul 133791, South Korea
[2] Hanyang Univ, Dept Chem Engn, Seoul 133791, South Korea
关键词
D O I
10.1002/adma.200703007
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A new, microfluidic polydiacetylene (PDA) sensor system based on the hydrodynamic focusing principle is developed. Narrow fluorescent bands are observed when the focused stream of a PDA solution contacts the sheath flows of cyclodextrin (CD) receptor molecules (see figure). The system allows for continuous and rapid monitoring of molecular recognition events.
引用
收藏
页码:1690 / +
页数:6
相关论文
共 50 条
[1]   ON THE ORIGIN OF THERMOCHROMISM IN CROSS-POLYMERIZED DIACETYLENE-FUNCTIONALIZED POLYAMIDES [J].
BECKHAM, HW ;
RUBNER, MF .
MACROMOLECULES, 1993, 26 (19) :5198-5201
[2]   Polydiacetylene films: a review of recent investigations into chromogenic transitions and nanomechanical properties [J].
Carpick, RW ;
Sasaki, DY ;
Marcus, MS ;
Eriksson, MA ;
Burns, AR .
JOURNAL OF PHYSICS-CONDENSED MATTER, 2004, 16 (23) :R679-R697
[3]   First observation of mechanochromism at the nanometer scale [J].
Carpick, RW ;
Sasaki, DY ;
Burns, AR .
LANGMUIR, 2000, 16 (03) :1270-1278
[4]   CHROMISM IN POLYDIACETYLENE SOLUTIONS AND CRYSTALS [J].
CHANCE, RR .
MACROMOLECULES, 1980, 13 (02) :396-398
[5]   Liquid crystals obtained from disclike mesogenic diacetylenes and their polymerization [J].
Chang, JY ;
Baik, JH ;
Lee, CB ;
Han, MJ ;
Hong, SK .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (13) :3197-3198
[6]   DIRECT COLORIMETRIC DETECTION OF A RECEPTOR-LIGAND INTERACTION BY A POLYMERIZED BILAYER ASSEMBLY [J].
CHARYCH, DH ;
NAGY, JO ;
SPEVAK, W ;
BEDNARSKI, MD .
SCIENCE, 1993, 261 (5121) :585-588
[7]   Coupling of an induced fit enzyme to polydiacetylene thin films: Colorimetric detection of glucose [J].
Cheng, Q ;
Stevens, RC .
ADVANCED MATERIALS, 1997, 9 (06) :481-&
[8]   Amino acid terminated polydiacetylene lipid microstructures: Morphology and chromatic transition [J].
Cheng, Q ;
Yamamoto, M ;
Stevens, RC .
LANGMUIR, 2000, 16 (12) :5333-5342
[9]   POLYMERIZATION OF DIACETYLENE CARBONIC-ACID MONOLAYERS AT GAS-WATER INTERFACE [J].
DAY, D ;
RINGSDORF, H .
JOURNAL OF POLYMER SCIENCE PART C-POLYMER LETTERS, 1978, 16 (05) :205-210
[10]   High-efficiency fluorescence quenching of conjugated polymers by proteins [J].
Fan, CH ;
Plaxco, KW ;
Heeger, AJ .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (20) :5642-5643