Activity of cathelicidin peptides against Chlamydia spp.

被引:27
作者
Donati, M
Di Leo, K
Benincasa, M
Cavrini, F
Accardo, S
Moroni, A
Gennaro, R
Cevenini, R
机构
[1] Univ Bologna, Policlin S Orsola, DMCSS, Sez Microbiol, I-40138 Bologna, Italy
[2] Univ Trieste, Dipartimento Biochim Biofis & Chim Macromol, I-34127 Trieste, Italy
关键词
D O I
10.1128/AAC.49.3.1201-1202.2005
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The in vitro activity of six cathelicidin peptides against 25 strains of Chlamydia was investigated. SMAP-29 proved to be the most active peptide, reducing the inclusion numbers of all 10 strains of Chlamydia trachomatis tested by greater than or equal to50% at 10 mug/ml. This peptide was also active against C. pneumoniae and C felis.
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收藏
页码:1201 / 1202
页数:2
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