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Limited value of endorectal magnetic resonance imaging and transrectal ultrasonography in the staging of clinically localized prostate cancer
被引:78
作者:
May, F
Treumann, T
Dettmar, P
Hartung, R
Breul, J
机构:
[1] Tech Univ Munich, Klinikum Rechts Isar, Dept Urol, D-81675 Munich, Germany
[2] Tech Univ Munich, Klinikum Rechts Isar, Dept Radiol, D-8000 Munich, Germany
[3] Tech Univ Munich, Klinikum Rechts Isar, Dept Pathol, D-8000 Munich, Germany
关键词:
prostate cancer;
staging;
MRI;
TRUS;
sensitivity;
specificity;
accuracy;
D O I:
10.1046/j.1464-410x.2001.00018.x
中图分类号:
R5 [内科学];
R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号:
1002 ;
100201 ;
摘要:
Objective To examine the role of endorectal magnetic resonance imaging (eMRI) and transrectal ultrasonography (TRUS) for clinically localized prostate cancer and to assess interobserver agreement in interpreting MRI studies. Patients and methods Fifty-four patients with biopsy-confirmed prostate cancer underwent TRUS and eMRI before radical retropubic prostatectomy. The MR images were prospectively interpreted by two radiologists with special expertise in this field. The criteria evaluated prospectively in each patient were extracapsular extension (ECE) and seminal vesicle invasion (SVI). The results were correlated with the histopathological findings after radical prostatectomy. Results At pathology, 27 patients had stage pT2, 15 had stage pT3a and 12 had stage pT3b lesions. The overall accuracy of eMRI in defining local tumour stage was 93% by radiologist A and 56% by radiologist B; the overall accuracy by TRUS was 63%. There was a poor correlation for the MRI studies between observers. The eMRI was more sensitive than TRUS for detecting ECE and SVI in organ-confined prostate cancer. TRUS had a relatively high specificity for ECE and SVI, and was better than eMRI in this regard. Conclusion Whereas MRT tended to over-stage, TRUS under-staged prostate cancer. This series shows the current limited value of TRUS and eMRI for planning treatment in patients with clinically localized prostate cancer. Treatment decisions should not be altered based on TRUS or eMRI findings alone.
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页码:66 / 69
页数:4
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