Synthesis of novel N-pyridylcantharidinimides by using high pressure

被引:6
作者
Lin, PY [1 ]
Shi, SJ [1 ]
Lin, LH [1 ]
Chen, HF [1 ]
Hsu, FL [1 ]
机构
[1] Taipei Med Univ, Sch Pharm, Taipei 250, Taiwan
关键词
cantharidinimide; cantharidin; aminopyridine;
D O I
10.1002/jccs.200100009
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The recently described pressure reaction in the presence of trithylamine with subsequent thermal (200 degreesC) cyclization provided 13N-pyridylcanthraidinimides 4a-4m from aminopyridines and cantharidin in yields of 15-83%. 2-Amino-3,5-dichloropyridine failed to yield 4n.
引用
收藏
页码:49 / 53
页数:5
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