Adding facets to TNF signaling: The JNK angle

被引：28

作者：

Liu, ZG ^{[1
]}

机构：

[1] NCI, Cell & Canc Biol Branch, Ctr Canc Res, NIH, Bethesda, MD 20892 USA

来源：

MOLECULAR CELL | 2003年 / 12卷 / 04期

关键词：

D O I：

10.1016/S1097-2765(03)00399-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In the October 3 issue of Cell, Deng et al. (2003) report that a JNK-dependent mitochondrial signal, the release of Smac/DIABLO, is required for TNF-induced caspase 8 activation and apoptosis. This process is interceded by a novel processed form of the BH3 only protein Bid.

引用

页码：795 / 796

页数：2

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