Altered Telomeres in Tumors with ATRX and DAXX Mutations

被引：824

作者：

Heaphy, Christopher M. ^{[1
]}

de Wilde, Roeland F. ^{[1
]}

Jiao, Yuchen

Klein, Alison P. ^{[1
]}

Edil, Barish H.

Shi, Chanjuan

Bettegowda, Chetan

Rodriguez, Fausto J. ^{[1
]}

Eberhart, Charles G. ^{[1
]}

Hebbar, Sachidanand ^{[1
]}

Offerhaus, G. Johan

McLendon, Roger

Rasheed, B. Ahmed

He, Yiping

Yan, Hai

Bigner, Darell D.

Oba-Shinjo, Sueli Mieko

Marie, Suely Kazue Nagahashi

Riggins, Gregory J.

Kinzler, Kenneth W.

Vogelstein, Bert

Hruban, Ralph H. ^{[1
]}

Maitra, Anirban ^{[1
]}

Papadopoulos, Nickolas

Meeker, Alan K. ^{[1
]}

机构：

[1] Johns Hopkins Med Inst, Dept Pathol, Sol Goldman Pancreat Canc Res Ctr, Baltimore, MD 21231 USA

来源：

SCIENCE | 2011年 / 333卷 / 6041期

关键词：

CELLS; H3.3;

D O I：

10.1126/science.1207313

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：425 / 425

页数：1

共 11 条

[1] Telomeric repeat-containing RNA and RNA surveillance factors at mammalian chromosome ends [J].

Azzalin, Claus M. ;

Reichenbach, Patrick ;

Khoriauli, Lela ;

Giulotto, Elena ;

Lingner, Joachim .

SCIENCE, 2007, 318 (5851) :798-801

[2] Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines [J].

Bryan, TM ;

Englezou, A ;

DallaPozza, L ;

Dunham, MA ;

Reddel, RR .

NATURE MEDICINE, 1997, 3 (11) :1271-1274

[3] HIRA and Daxx Constitute Two Independent Histone H3.3-Containing Predeposition Complexes [J].

Elsaesser, S. J. ;

Allis, C. D. .

NUCLEAR ORGANIZATION AND FUNCTION, 2010, 75 :27-34

[4] Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions [J].

Goldberg, Aaron D. ;

Banaszynski, Laura A. ;

Noh, Kyung-Min ;

Lewis, Peter W. ;

Elsaesser, Simon J. ;

Stadler, Sonja ;

Dewell, Scott ;

Law, Martin ;

Guo, Xingyi ;

Li, Xuan ;

Wen, Duancheng ;

Chapgier, Ariane ;

DeKelver, Russell C. ;

Miller, Jeffrey C. ;

Lee, Ya-Li ;

Boydston, Elizabeth A. ;

Holmes, Michael C. ;

Gregory, Philip D. ;

Greally, John M. ;

Rafii, Shahin ;

Yang, Chingwen ;

Scambler, Peter J. ;

Garrick, David ;

Gibbons, Richard J. ;

Higgs, Douglas R. ;

Cristea, Ileana M. ;

Urnov, Fyodor D. ;

Zheng, Deyou ;

Allis, C. David .

CELL, 2010, 140 (05) :678-691

[5] DAXX/ATRX, MEN1, and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors [J].

Jiao, Yuchen ;

Shi, Chanjuan ;

Edil, Barish H. ;

de Wilde, Roeland F. ;

Klimstra, David S. ;

Maitra, Anirban ;

Schulick, Richard D. ;

Tang, Laura H. ;

Wolfgang, Christopher L. ;

Choti, Michael A. ;

Velculescu, Victor E. ;

Diaz, Luis A., Jr. ;

Vogelstein, Bert ;

Kinzler, Kenneth W. ;

Hruban, Ralph H. ;

Papadopoulos, Nickolas .

SCIENCE, 2011, 331 (6021) :1199-1203

[6] ATR-X Syndrome Protein Targets Tandem Repeats and Influences Allele-Specific Expression in a Size-Dependent Manner [J].

Law, Martin J. ;

Lower, Karen M. ;

Voon, Hsiao P. J. ;

Hughes, Jim R. ;

Garrick, David ;

Viprakasit, Vip ;

Mitson, Matthew ;

De Gobbi, Marco ;

Marra, Marco ;

Morris, Andrew ;

Abbott, Aaron ;

Wilder, Steven P. ;

Taylor, Stephen ;

Santos, Guilherme M. ;

Cross, Joe ;

Ayyub, Helena ;

Jones, Steven ;

Ragoussis, Jiannis ;

Rhodes, Daniela ;

Dunham, Ian ;

Higgs, Douglas R. ;

Gibbons, Richard J. .

CELL, 2010, 143 (03) :367-378

[7] Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres [J].

Lewis, Peter W. ;

Elsaesser, Simon J. ;

Noh, Kyung-Min ;

Stadler, Sonja C. ;

Allis, C. David .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (32) :14075-14080

[8] ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells [J].

Wong, Lee H. ;

McGhie, James D. ;

Sim, Marcus ;

Anderson, Melissa A. ;

Ahn, Soyeon ;

Hannan, Ross D. ;

George, Amee J. ;

Morgan, Kylie A. ;

Mann, Jeffrey R. ;

Choo, K. H. Andy .

GENOME RESEARCH, 2010, 20 (03) :351-360

[9] Histone H3.3 incorporation provides a unique and functionally essential telomeric chromatin in embryonic stem cells [J].

Wong, Lee H. ;

Ren, Hua ;

Williams, Evan ;

McGhie, James ;

Ahn, Soyeon ;

Sim, Marcus ;

Tam, Angela ;

Earle, Elizabeth ;

Anderson, Melissa A. ;

Mann, Jeffrey ;

Choo, K. H. Andy .

GENOME RESEARCH, 2009, 19 (03) :404-414

[10] The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodies [J].

Xue, YT ;

Gibbons, R ;

Yan, ZJ ;

Yang, DF ;

McDowell, TL ;

Sechi, S ;

Qin, J ;

Zhou, SL ;

Higgs, D ;

Wang, WD .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (19) :10635-10640

← 1 2 →