Successful treatment of ventricular assist device associated ventricular thrombus with systemic tenecteplase

被引：15

作者：

Hayes, H. ^{[1
]}

Dembo, L. ^{[1
]}

Larbalestier, R. ^{[1
]}

O'Driscoll, G. ^{[1
,2
,3
]}

机构：

[1] Royal Perth Hosp, Adv Heart Failure & Cardiac Transplant Serv, Perth, WA, Australia

[2] Univ Notre Dame, Sch Med, Fremantle, WA, Australia

[3] Univ Western Australia, Dept Human Movement & Exercise Sci, Nedlands, WA 6009, Australia

来源：

HEART LUNG AND CIRCULATION | 2008年 / 17卷 / 03期

关键词：

Jarvik 2000 Flowmaker (R); thrombus; tenecteplase;

D O I：

10.1016/j.hlc.2007.04.012

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report a case of intracardiac thrombus in a patient supported by the Jarvik 2000 Flowmaker (R) successfully treated with a single dose of peripherally administered TNK-tissue plasminogen activator (Tenecteplase, Metalyse (R), Boehringer Ingelheim). This strategy may be considered in the case of life-threatening VAD associated thrombosis to avoid the need for intracardiac drug delivery or VAD replacement. We also discuss the apparent increased thrombotic risk in patients receiving a VAD for chemotherapy induced cardiomyopathy and the implications this may have for the choice of VAD.

引用

页码：253 / 255

页数：3

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