Ag@AgI, Core@Shell Structure in Agarose Matrix as Hybrid: Synthesis, Characterization, and Antimicrobial Activity

被引：48

作者：

Ghosh, Somnath ^{[1
]}

Saraswathi, A. ^{[1
]}

Indi, S. S. ^{[2
]}

Hoti, S. L. ^{[3
]}

Vasan, H. N. ^{[1
]}

机构：

[1] Indian Inst Sci, Solid State & Struct Chem Unit, Bangalore 560012, Karnataka, India

[2] Indian Inst Sci, Dept Microbiol & Cell Biol, Bangalore 560012, Karnataka, India

[3] Vector Control Res Ctr, Pondicherry 605006, India

来源：

LANGMUIR | 2012年 / 28卷 / 22期

关键词：

ESCHERICHIA-COLI; ANTIBACTERIAL ACTIVITY; SILVER NANOPARTICLES; DRINKING-WATER; BACTERIAL BIOFILMS; OPTICAL-PROPERTIES; IN-SITU; NANOCOMPOSITES; DISINFECTION; GENERATION;

D O I：

10.1021/la301322j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel in situ core@shell structure consisting of nanoparticles of Ag (Ag Nps) and AgI in agarose matrix (Ag@ AgI/agarose) has been synthesized as a hybrid, in order to have an efficient antibacterial agent for repetitive usage with no toxicity. The synthesized core@shell structure is very well characterized by XRD, UV-visible, photoluminescence, and TEM. A detailed antibacterial studies including repetitive cycles are carried out on Gram-negative Escherichia coli (E. coli) and Gram-positive Staphylococcus aureus (S. aureus) bacteria in saline water, both in dark and on exposure to visible light. The hybrid could be recycled for the antibacterial activity and is nontoxic toward human cervical cancer cells (HeLa cells). The water insoluble Ag@AgI in agarose matrix forms a good coating on quartz, having good mechanical strength. EPR and TEM studies are carried out on the Ag@AgI/agarose and the bacteria, respectively, to elucidate a possible mechanism for killing of the bacteria.

引用

页码：8550 / 8561

页数：12

共 81 条

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