Analysis of nitrofuran metabolites in food by high-performance liquid chromatography with tandem mass spectrometry detection

被引：19

作者：

Edder, P ^{[1
]}

Vargas, S ^{[1
]}

Ortelli, D ^{[1
]}

Corvi, C ^{[1
]}

机构：

[1] Serv Protect Consommat, CH-1205 Geneva, Switzerland

来源：

CLINICAL CHEMISTRY AND LABORATORY MEDICINE | 2003年 / 41卷 / 12期

关键词：

antibiotic residues; food; LC-MS/MS; nitrofurans;

D O I：

10.1515/CCLM.2003.244

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

A reliable and sensitive procedure is presented for the analysis of nitrofuran metabolite residues in foods of animal origin, like poultry and shrimp. The method is based on a onestep extraction/derivatization, followed by solidphase extraction cleanup with polymeric phase cartridges. The separations were carried out by liquid chromatography coupled with tandem mass spectroscopy detection. Results from the full validation of the procedure and from a survey of food available from the Swiss market, with the analysis of 236 samples of shrimp, poultry, fish and rabbit, are presented and demonstrate that this method is satisfactory in order to control nitrofuran residues in foods of animal origin.

引用

收藏

页码：1608 / 1614

页数：7

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