The Anopheles gambiae genome:: an update

被引:54
作者
Mongin, E
Louis, C
Holt, RA
Birney, E
Collins, FH
机构
[1] Univ Notre Dame, Ctr Trop Dis Res & Training, Notre Dame, IN 46556 USA
[2] Tech Univ Hamburg, Dept Mol & Cellular Biol, Cambridge, MA 02138 USA
[3] Fdn Res & Technol Hellas, Inst Mol Biol & Biotechnol, GR-71110 Iraklion, Crete, Greece
[4] European Mol Biol Lab, European Bioinformat Inst, Cambridge CB10 1SD, England
关键词
D O I
10.1016/j.pt.2003.11.003
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
As a result of an international collaborative effort, the first draft of the Anopheles gambiae genome sequence and its preliminary annotation were published in October 2002. Since then, the assembly, annotation and means of accession of the An. gambiae genome have been under continuous development. This article reviews progress and considers limitations in the current sequence assembly and gene annotation, as well as approaches to address these problems and outstanding issues that users of the data must bear in mind.
引用
收藏
页码:49 / 52
页数:4
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