PRINTS and its automatic supplement, prePRINTS

被引:251
作者
Attwood, TK [1 ]
Bradley, P
Flower, DR
Gaulton, A
Maudling, N
Mitchell, AL
Moulton, G
Nordle, A
Paine, K
Taylor, P
Uddin, A
Zygouri, C
机构
[1] Univ Manchester, Sch Biol Sci, Manchester M13 9PT, Lancs, England
[2] Univ Manchester, Dept Comp Sci, Manchester M13 9PT, Lancs, England
[3] European Bioinformat Inst, EMBL Outstn, Cambridge CB10 1SD, England
[4] Edward Jenner Inst Vaccine Res, Newbury RG20 7NN, Berks, England
基金
英国工程与自然科学研究理事会; 英国生物技术与生命科学研究理事会; 英国医学研究理事会;
关键词
D O I
10.1093/nar/gkg030
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The PRINTS database houses a collection of protein fingerprints. These may be used to assign uncharacterised sequences to known families and hence to infer tentative functions. The September 2002 release ( version 36.0) includes 1800 fingerprints, encoding similar to 11 000 motifs, covering a range of globular and membrane proteins, modular polypeptides and so on. In addition to its continued steady growth, we report here the development of an automatic supplement, prePRINTS, designed to increase the coverage of the resource and reduce some of the manual burdens inherent in its maintenance. The databases are accessible for interrogation and searching at http: / / www. bioinf. man. ac. uk/ dbbrowser/ PRINTS/.
引用
收藏
页码:400 / 402
页数:3
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