Cell and molecular biology of Notch

被引：324

作者：

Fiuza, Ulla-Maj ^{[1
]}

Arias, Alfonso Martinez ^{[1
]}

机构：

[1] Univ Cambridge, Dept Genet, Cambridge CB2 3EH, England

来源：

JOURNAL OF ENDOCRINOLOGY | 2007年 / 194卷 / 03期

基金：

英国惠康基金;

关键词：

D O I：

10.1677/JOE-07-0242

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Notch signalling is a cell-cell communication process, which allows the establishment of patterns of gene expression and differentiation, regulates binary cell fate choice and the maintenance of stern cell populations. So far, the data published has elucidated the main players in the Notch signalling pathway. However, its regulatory mechanisms are exhibiting an increasing complexity which could account for the multitude of roles it has during development and in adult organisms. In this review, we will describe the multiple roles of Notch and how various factors can regulate Notch signalling.

引用

收藏

页码：459 / 474

页数：16

相关论文

共 144 条

[1]

Alagille syndrome - A notch up for the Notch receptor [J].

ArtavanisTsakonas, S .

NATURE GENETICS, 1997, 16 (03) :212-213

[2]

Wnt3A plays a major role in the segmentation clock controlling somitogenesis [J].

Aulehla, A ;

Wehrle, C ;

Brand-Saberi, B ;

Kemler, R ;

Gossler, A ;

Kanzler, B ;

Herrmann, BG .

DEVELOPMENTAL CELL, 2003, 4 (03) :395-406

[3]

Interaction between wingless and notch signaling pathways mediated by dishevelled [J].

Axelrod, JD ;

Matsuno, K ;

ArtavanisTsakonas, S ;

Perrimon, N .

SCIENCE, 1996, 271 (5257) :1826-1832

[4]

Bearded family members inhibit neuralized-mediated endocytosis and signaling activity of Delta in Drosophila [J].

Bardin, AJ ;

Schweisguth, F .

DEVELOPMENTAL CELL, 2006, 10 (02) :245-255

[5]

Default repression and Notch signaling: Hairless acts as an adaptor to recruit the corepressors Groucho and dCtBP to Suppressor of Hairless [J].

Barolo, S ;

Stone, T ;

Bang, AG ;

Posakony, JW .

GENES & DEVELOPMENT, 2002, 16 (15) :1964-1976

[6]

Interaction between Notch signalling and Lunatic fringe during somite boundary formation in the mouse [J].

Barrantes, ID ;

Elia, AJ ;

Wünsch, K ;

De Angelis, MH ;

Mak, TW ;

Rossant, J ;

Conlon, RA ;

Gossler, A ;

de la Pompa, JL .

CURRENT BIOLOGY, 1999, 9 (09) :470-480

[7]

Par-1 kinase establishes cell polarity and functions in Notch signaling in the Drosophila embryo [J].

Bayraktar, J ;

Zygmunt, D ;

Carthew, RW .

JOURNAL OF CELL SCIENCE, 2006, 119 (04) :711-721

[8]

Notch signalling in Drosophila:: three ways to use a pathway [J].

Bray, S .

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 1998, 9 (06) :591-597

[9]

Wingless modulates the effects of dominant negative notch molecules in the developing wing of Drosophila [J].

Brennan, K ;

Klein, T ;

Wilder, E ;

Arias, AM .

DEVELOPMENTAL BIOLOGY, 1999, 216 (01) :210-229

[10]

The Abruptex mutations of Notch disrupt the establishment of proneural clusters in Drosophila [J].

Brennan, K ;

Tateson, R ;

Lieber, T ;

Couso, JP ;

Zecchini, V ;

Arias, AM .

DEVELOPMENTAL BIOLOGY, 1999, 216 (01) :230-242

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