Trifluoromethylation of carbonyl compounds with sodium trifluoroacetate

被引：48

作者：

Chang, Y ^{[1
]}

Cai, C ^{[1
]}

机构：

[1] Nanjing Univ Sci & Technol, Sch Chem Engn, Nanjing 210094, Peoples R China

来源：

JOURNAL OF FLUORINE CHEMISTRY | 2005年 / 126卷 / 06期

关键词：

trifluoromethylation; sodium trifluoroacetate; carbonyl compounds; mechanism;

D O I：

10.1016/j.jfluchem.2005.04.012

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

In the presence of copper(l) iodide as catalyst, a variety of carbonyl compounds, such as aldehydes, ketones and acid anhydrous, could be trifluoromethylated with sodium trifluoroacetate to give the corresponding alcohols in moderate to high yields, and a possible mechanism was proposed to explain the roles of catalyst and solvent in the reaction system. (C) 2005 Elsevier B.V. All rights reserved.

引用

页码：937 / 940

页数：4

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