Extractive biocatalysis: a powerful tool in selectivity control in yeast biotransformations

被引：46

作者：

D'Arrigo, P

Fuganti, C

Fantoni, GP

Servi, S

机构：

[1] Politecn Milan, Ctr Studio Sostanze Organ Nat, CNR, I-20131 Milan, Italy

[2] Politecn Milan, Dipartimento Chim, I-20131 Milan, Italy

来源：

TETRAHEDRON | 1998年 / 54卷 / 49期

关键词：

baker's yeast; reduction; absorbing resins; in situ product removal;

D O I：

10.1016/S0040-4020(98)00941-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The effect of absorbing resins on the yeast reduction of cl,P-unsaturated carbonyl compounds is reported. Enantioselectivity, chemoselectivity and space-time yields of the biotransformation are impressively enhanced. The distribution of substrates and products between the resin and the water phase shows that the improved selectivity has to be attributed to the control of substrate concentration, (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：15017 / 15026

页数：10

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