Identification of NAP-22 and GAP-43 (neuromodulin) as major protein components in a Triton insoluble low density fraction of rat brain

被引：49

作者：

Maekawa, S

Kumanogoh, H

Funatsu, N

Takei, N

Inoue, K

Endo, Y

Hamada, K

Sokawa, Y

机构：

[1] Department of Biotechnology, Faculty of Textile Science, Kyoto Institute of Technology

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES | 1997年 / 1323卷 / 01期

关键词：

GAP-43; neuromodulin; NAP-22; G protein; triton insoluble; membrane; (rat brain);

D O I：

10.1016/S0005-2736(96)00222-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

NAP-22 is a membrane-localized brain enriched acidic protein having a Ca2+-dependent calmodulin binding activity. Further fractionation of the NAP-22 containing membrane showed the localization of NAP-22 in a Triton insoluble fraction of low density. Besides NAP-22, this fraction was found to contain GAP-43 (neuromodulin), trimeric G proteins, and some GPI-anchored proteins such as Thy-1 and N-CAM-120. Presence of some protein tyrosine kinases, such as src and fyn, was also shown.

引用

页码：1 / 5

页数：5

共 13 条

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