Fractal methods and results in cellular morphology - Dimensions, lacunarity and multifractals

被引:461
作者
Smith, TG
Lange, GD
Marks, WB
机构
[1] NINCDS, INSTRUMENTAT & COMP SECT, NIH, BETHESDA, MD 20892 USA
[2] NINCDS, NEURAL CONTROL LAB, NIH, BETHESDA, MD 20892 USA
关键词
fractal geometry; fractal dimension; lacunarity; multifractal; self-similarity; cell borders;
D O I
10.1016/S0165-0270(96)00080-5
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
This paper discusses the concepts of fractal geometry in a cellular biological context. It defines the concept of the fractal dimension, D, as a measure of complexity and illustrates the two different general ways of quantitatively measuring D by length-related and mass-related methods. Then, these several Ds are compared and contrasted. A goal of the paper is to find methods other than length-related measures that can distinguish between two objects that have the same D but are structurally different. The mass-related D is shown potentially to be such a measure. The concept of lacunarity, L, is defined and methods of measuring L are illustrated. L is also shown to be a potentially distinguishing measure. Finally, the notion of multifracticality is defined and illustrated to exist in certain individual nerve and glial cells.
引用
收藏
页码:123 / 136
页数:14
相关论文
共 31 条
[21]  
Reichenbach A, 1992, Neuroimage, V1, P69, DOI 10.1016/1053-8119(92)90008-B
[22]  
Russ J.C., 1994, FRACTAL SURFACES
[23]  
SENITZ D, 1995, J BRAIN RES, V36, P531
[24]  
SIEGEL A, 1991, ANAT EMBRYOL, V183, P605
[25]   A FRACTAL ANALYSIS OF CULTURED RAT OPTIC-NERVE GLIAL GROWTH AND DIFFERENTIATION [J].
SMITH, TG ;
BEHAR, TN ;
LANGE, GD ;
MARKS, WB ;
SHERIFF, WH .
NEUROSCIENCE, 1991, 41 (01) :159-166
[26]   COMPARATIVE FRACTAL ANALYSIS OF CULTURED GLIA DERIVED FROM OPTIC-NERVE AND BRAIN DEMONSTRATE DIFFERENT RATES OF MORPHOLOGICAL-DIFFERENTIATION [J].
SMITH, TG ;
BEHAR, TN .
BRAIN RESEARCH, 1994, 634 (02) :181-190
[27]   A FRACTAL ANALYSIS OF CELL IMAGES [J].
SMITH, TG ;
MARKS, WB ;
LANGE, GD ;
SHERIFF, WH ;
NEALE, EA .
JOURNAL OF NEUROSCIENCE METHODS, 1989, 27 (02) :173-180
[28]  
SMITH TG, 1996, FRACTAL GEOMETRY BIO, P173
[29]  
SMITH TG, 1994, P 1 INT S FRACT BIOL, P210
[30]  
TAUTU P, 1994, P 1 INT S FRACT BIOL, P86