Fc receptors and immunity to parasites

被引：53

作者：

Pleass, RJ ^{[1
]}

Woof, JM ^{[1
]}

机构：

[1] Univ Dundee, Ninewells Hosp, Sch Med, Dept Mol & Cellular Pathol, Dundee DD1 9SY, Scotland

来源：

TRENDS IN PARASITOLOGY | 2001年 / 17卷 / 11期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/S1471-4922(01)02086-4

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Fc receptors (FcRs) are crucial in the immune system; they mediate a plethora of biological functions as diverse as antigen presentation, phagocytosis, cytotoxicity, induction of inflammatory cascades and modulation of immune responses. Parasites, in order to survive in the immunocompetent host, have devised ingenious methods to subvert this important aspect of the immune response. This article discusses the current thinking on FcRs,their role in immunity to parasites, and immune evasion strategies employed by parasites in their attempt to neutralize the important immune defense mechanisms mediated by these molecules.

引用

页码：545 / 551

页数：9

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