Dendritic cells in peripheral tolerance and immunity

被引:37
作者
Gad, M [1 ]
Claesson, MH [1 ]
Pedersen, AE [1 ]
机构
[1] Univ Copenhagen, Panum Inst, Dept Med Anat, Cellular Immunol Lab, DK-2200 Copenhagen, Denmark
关键词
dendritic cells; tolerance; immunity; toll-like receptors; regulatory T cells;
D O I
10.1034/j.1600-0463.2003.11107808.x
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Dendritic cells capable of influencing immunity exist as functionally distinct subsets, T cell-tolerizing and T cell-immunizing subsets. The present paper reviews how these subsets of DCs develop, differentiate and function in vivo and in vitro at the cellular and molecular level. In particular, the role of DCs in the generation of regulatory T cells is highlighted.
引用
收藏
页码:766 / 775
页数:10
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