Engineering bacteria for bioremediation

被引:271
作者
Pieper, DH
Reineke, W
机构
[1] Gesell Biotechnol Forsch mbH, Dept Environm Biotechnol, D-38124 Braunschweig, Germany
[2] Berg Univ Wuppertal, D-42097 Wuppertal, Germany
关键词
D O I
10.1016/S0958-1669(00)00094-X
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The treatment of environmental pollution by microorganisms is a promising technology. Various genetic approaches have been developed and used to optimize the enzymes, metabolic pathways and organisms relevant for biodegradation, New information on the metabolic routes and bottlenecks of degradation is still accumulating. enlarging the available toolbox. With molecular methods allowing the characterization of microbial community structure and activities, the performance of microorganisms under in situ conditions and in concert with the indigenous microflora will become predictable.
引用
收藏
页码:262 / 270
页数:9
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共 85 条
[31]   Bacteria tolerant to organic solvents [J].
Isken, S ;
de Bont, JAM .
EXTREMOPHILES, 1998, 2 (03) :229-238
[32]   A high-throughput digital imaging screen for the discovery and directed evolution of oxygenases [J].
Joo, H ;
Arisawa, A ;
Lin, ZL ;
Arnold, FH .
CHEMISTRY & BIOLOGY, 1999, 6 (10) :699-706
[33]   Laboratory evolution of peroxide-mediated cytochrome P450 hydroxylation [J].
Joo, H ;
Lin, ZL ;
Arnold, FH .
NATURE, 1999, 399 (6737) :670-673
[34]   Involvement of the cis/trans isomerase Cti in solvent resistance of Pseudomonas putida DOT-T1E [J].
Junker, F ;
Ramos, JL .
JOURNAL OF BACTERIOLOGY, 1999, 181 (18) :5693-5700
[35]   Structure of an aromatic-ring-hydroxylating dioxygenase-naphthalene 1,2-dioxygenase [J].
Kauppi, B ;
Lee, K ;
Carredano, E ;
Parales, RE ;
Gibson, DT ;
Eklund, H ;
Ramaswamy, S .
STRUCTURE, 1998, 6 (05) :571-586
[36]   Novel family shuffling methods for the in vitro evolution of enzymes [J].
Kikuchi, M ;
Ohnishi, K ;
Harayama, S .
GENE, 1999, 236 (01) :159-167
[37]   Functional analyses of a variety of chimeric dioxygenases constructed from two biphenyl dioxygenases that are similar structurally but different functionally [J].
Kimura, N ;
Nishi, A ;
Goto, M ;
Furukawa, K .
JOURNAL OF BACTERIOLOGY, 1997, 179 (12) :3936-3943
[38]   Outer membrane changes in a toluene-sensitive mutant of toluene-tolerant Pseudomonas putida IH-2000 [J].
Kobayashi, H ;
Takami, H ;
Hirayama, H ;
Kobata, K ;
Usami, R ;
Horikoshi, K .
JOURNAL OF BACTERIOLOGY, 1999, 181 (15) :4493-4498
[39]   Enhanced degradation of polychlorinated biphenyls by directed evolution of biphenyl dioxygenase [J].
Kumamaru, T ;
Suenaga, H ;
Mitsuoka, M ;
Watanabe, T ;
Furukawa, K .
NATURE BIOTECHNOLOGY, 1998, 16 (07) :663-666
[40]   Engineering a recombinant Deinococcus radiodurans for organopollutant degradation in radioactive mixed waste environments [J].
Lange, CC ;
Wackett, LP ;
Minton, KW ;
Daly, MJ .
NATURE BIOTECHNOLOGY, 1998, 16 (10) :929-933