MRSA in livestock animals - an epidemic waiting to happen?

被引：147

作者：

Wulf, M. ^{[2
]}

Voss, A. ^{[1
,3
]}

机构：

[1] Radboud Univ Nijmegen, Med Ctr, Dept Med Microbiol, Nijmegen Univ Ctr Infect Dis, NL-6525 ED Nijmegen, Netherlands

[2] PAMM Lab Med Microbiol, Veldhoven, Netherlands

[3] Canisius Wilhelmina Hosp, Dept Med Microbiol & Infect Dis, Nijmegen, Netherlands

来源：

CLINICAL MICROBIOLOGY AND INFECTION | 2008年 / 14卷 / 06期

关键词：

community-acquired MRSA; epidemiology; livestock; methicillin-resistant Staphylococcus aureus; pig farming; ST398;

D O I：

10.1111/j.1469-0691.2008.01970.x

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Screening of pig farmers and pigs in The Netherlands has revealed that > 20% of pig farmers and 39% of slaughterhouse pigs are positive for an unusual strain of methicillin-resistant Staphylococcus aureus (MRSA) belonging to sequence type (ST) 398. It is now clear that the emergence of ST398 is not just a Dutch problem, with human infections being described in several European countries, Canada and Singapore. Furthermore, some human isolates have now acquired the genes encoding Panton-Valentine leukocidin. Livestock may become an important source of community-acquired MRSA. A concerted effort on the part of clinicians, infection control practitioners and veterinarians will be required to prevent further spread of this novel strain of MRSA.

引用

页码：519 / 521

页数：3

共 11 条

[1] Clonal comparison of Staphylococcus aureus isolates from healthy pig farmers, human controls, and pigs [J].

Armand-Lefevre, L ;

Ruimy, R ;

Andremont, A .

EMERGING INFECTIOUS DISEASES, 2005, 11 (05) :711-714

[2] Presence of a novel DNA methylation enzyme in methicillin-resistant Staphylococcus aureus isolates associated with pig farming leads to uninterpretable results in standard pulsed-field gel electrophoresis analysis [J].

Bens, Corina C. P. M. ;

Voss, Andreas ;

Klaassen, Corne H. W. .

JOURNAL OF CLINICAL MICROBIOLOGY, 2006, 44 (05) :1875-1876

[3] High prevalence of methicillin resistant Staphylococcus aureus in pigs [J].

de Neeling, A. J. ;

van den Broek, M. J. M. ;

Spalburg, E. C. ;

van Santen-Verheuvel, M. G. ;

Dam-Deisz, W. D. C. ;

Boshuizen, H. C. ;

de Giessen, A. W. van ;

van Duijkeren, E. ;

Huijsdens, X. W. .

VETERINARY MICROBIOLOGY, 2007, 122 (3-4) :366-372

[4]

Ekkelenkamp M B, 2006, Ned Tijdschr Geneeskd, V150, P2442

[5] Community-acquired MRSA and pig-farming [J].

Huijsdens X.W. ;

van Dijke B.J. ;

Spalburg E. ;

van Santen-Verheuvel M.G. ;

Heck M.E.O.C. ;

Pluister G.N. ;

Voss A. ;

Wannet W.J.B. ;

de Neeling A.J. .

Annals of Clinical Microbiology and Antimicrobials, 5 (1)

[6] Transmission of methicillin-resistant Staphylococcus aureus strains between different kinds of pig farms [J].

van Duijkeren, E. ;

Ikawaty, R. ;

Broekhuizen-Stins, M. J. ;

Jansen, M. D. ;

Spalburg, E. C. ;

de Neeling, A. J. ;

Allaart, J. G. ;

van Nes, A. ;

Wagenaar, J. A. ;

Fluit, A. C. .

VETERINARY MICROBIOLOGY, 2008, 126 (04) :383-389

[7] Emergence of methicillin-resistant Staphylococcus aureus of animal origin in humans [J].

van Loo, Inge ;

Huijsdens, Xander ;

Tiemersma, Edine ;

de Neeling, Albert ;

van de Sande-Bruinsma, Nienke ;

Beaujean, Desiree ;

Voss, Andreas ;

Kluytmans, Jan .

EMERGING INFECTIOUS DISEASES, 2007, 13 (12) :1834-1839

[8] Increase in a Dutch hospital of methicillin-resistant Staphylococcus aureus related to animal farming [J].

van Rijen, Miranda Maria Lucia ;

Van Keulen, Peter H. ;

Kluytmans, Jan A. .

CLINICAL INFECTIOUS DISEASES, 2008, 46 (02) :261-263

[9] Methicillin-resistant Staphylococcus aureus in pig farming [J].

Voss, A ;

Loeffen, F ;

Bakker, J ;

Klaassen, C ;

Wulf, M .

EMERGING INFECTIOUS DISEASES, 2005, 11 (12) :1965-1966

[10] Methicillin-resistant Staphylococcus aureus ST398 in humans and animals, Central Europe [J].

Witte, Wolfgang ;

Strommenger, Birgit ;

Stanek, Christian ;

Cuny, Christiane .

EMERGING INFECTIOUS DISEASES, 2007, 13 (02) :255-258

← 1 2 →