A porphyrin tetramer for a positive homotropic allosteric recognition system: efficient binding information transduction through butadiynyl axis rotation

被引：22

作者：

Kubo, Y ^{[1
]}

Ikeda, M ^{[1
]}

Sugasaki, A ^{[1
]}

Takeuchi, M ^{[1
]}

Shinkai, S ^{[1
]}

机构：

[1] Kyushu Univ, Grad Sch Engn, Dept Chem & Biochem, Fukuoka 8128581, Japan

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 42期

关键词：

porphyrin; cooperativity; allosterism; molecular recognition; rotational axis;

D O I：

10.1016/S0040-4039(01)01546-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A porphyrin tetramer 1 was newly designed and synthesized to construct a novel allosteric guest-binding system. Compound 1 has a butadiynyl rotational axis. which is expected to act as a guest-binding information transducer. In chloroform., 1 can bind bidentate amines, such as 1.3-di(4-piperidyl)propane (DPP), in an allosteric manner to produce a 1:2 1/diamine complex with a Hill coefficient of 1.9. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：7435 / 7438

页数：4

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