Consensus statement of the European Group on Graves' orbitopathy (EUGOGO) on management of GO

被引：501

作者：

Bartalena, Luigi ^{[1
,2
]}

Baldeschi, Lelio

Dickinson, Alison ^{[3
]}

Eckstein, Anja ^{[4
]}

Kendall-Taylor, Pat ^{[5
]}

Marcocci, Claudio ^{[6
]}

Mourits, Maarten ^{[7
]}

Perros, Petros ^{[8
]}

Boboridis, Kostas ^{[9
]}

Boschi, Antonella ^{[10
]}

Curro, Nicola ^{[11
]}

Daumerie, Chantal ^{[12
]}

Kahaly, George J. ^{[13
]}

Krassas, Gerasimos E. ^{[14
]}

Lane, Carol M. ^{[15
]}

Lazarus, John H. ^{[16
]}

Marino, Michele ^{[6
]}

Nardi, Marco ^{[17
]}

Neoh, Christopher ^{[3
]}

Orgiazzi, Jacques ^{[18
]}

Pearce, Simon ^{[19
]}

Pinchera, Aldo ^{[6
]}

Pitz, Susanne ^{[20
]}

Salvi, Mario ^{[21
]}

Sivelli, Paolo ^{[22
]}

Stahl, Matthias ^{[23
]}

von Arx, Georg ^{[24
]}

Wiersinga, Wilmar M. ^{[25
]}

机构：

[1] Univ Insubria, Dept Clin Med, I-21100 Varese, Italy

[2] Acad Med Ctr, Dept Ophthalmol, NL-1100 DD Amsterdam, Netherlands

[3] Royal Victoria Infirm, Dept Ophthalmol, Newcastle Upon Tyne NE1 4LP, Tyne & Wear, England

[4] Univ Essen Gesamthsch, Dept Ophthalmol, D-45122 Essen, Germany

[5] Newcastle Univ, Sch Med, Newcastle Upon Tyne NE1 4LP, Tyne & Wear, England

[6] Univ Pisa, Dept Endocrinol, I-56124 Pisa, Italy

[7] Acad Med Ctr, Orbital Ctr, Dept Ophthalmol, NL-1100 DD Amsterdam, Netherlands

[8] Freeman Rd Hosp, Dept Endocrinol, Newcastle Upon Tyne NE1 4LP, Tyne & Wear, England

[9] Ahepa Hosp, Dept Ophthalmol, Thessaloniki 55132, Greece

[10] Catholic Univ Louvain, Dept Ophthalmol, B-1200 Brussels, Belgium

[11] Univ Milan, Dept Ophthalmol, I-20100 Milan, Italy

[12] Catholic Univ Louvain, Clin Univ, B-1200 Brussels, Belgium

[13] Gutenberg Univ Hosp, Dept Med 1, D-55131 Mainz, Germany

[14] Panagia Gen Hosp, Dept Endocrinol, Thessaloniki 55132, Greece

[15] Univ Wales Hosp, Cardiff Eye Unit, Cardiff CF64 4XX, Wales

[16] Cardiff Univ, Llandough Hosp, Sch Med, Cardiff CF64 4XX, Wales

[17] Univ Pisa, Sect Ophthalmol, Dept Neurosci, I-56124 Pisa, Italy

[18] Ctr Hosp Lyon Sud, Dept Endocrinol, Lyon, France

[19] Univ Newcastle, Sch Clin Med Sci, Newcastle Upon Tyne NE1 4LP, Tyne & Wear, England

[20] Johannes Gutenberg Univ Mainz, Dept Ophthalmol, D-55131 Mainz, Germany

[21] Univ Milan, Dept Med Sci, I-20100 Milan, Italy

[22] Univ Insubria, Dept Ophthalmol, I-21100 Varese, Italy

[23] Solothurner Spitaler, Dept Endocrinol, CH-4600 Olten, Switzerland

[24] Interdisziplinares Zentrum Endokrine Orbitopathie, CH-4600 Olten, Switzerland

[25] Acad Med Ctr, Dept Endocrinol, NL-1100 DD Amsterdam, Netherlands

来源：

EUROPEAN JOURNAL OF ENDOCRINOLOGY | 2008年 / 158卷 / 03期

关键词：

D O I：

10.1530/EJE-07-0666

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

a. All patients with GO should (Fig. 1): Be referred to specialist centers; Be encouraged to quit smoking; Receive prompt treatment in order to restore and maintain euthyroidism. b. Patients with sight-threatening GO should be treated with i.v. GCs as the first-line treatment; if the response is poor after 1-2 weeks, they should be submitted to urgent surgical decompression. c. The treatment of choice for moderate-to-severe GO is i.v. GCs (with or without OR) if the orbitopathy is active; surgery (orbital decompression, squint surgery, and/or eyelid surgery in this order) should be considered if the orbitopathy is inactive. d. In patients with mild GO, local measures and an expectant strategy are sufficient in most cases, but treatment may be justified if QoL is affected significantly. © 2008 Society of the European Journal of Endocrinology.

引用

页码：273 / 285

页数：13

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