A general and versatile molecular design for host molecules working in water: a duplex-based potassium sensor consisting of three functional regions

被引：28

作者：

Fujimoto, K ^{[1
]}

Muto, Y ^{[1
]}

Inouye, M ^{[1
]}

机构：

[1] Toyama Med & Pharmaceut Univ, Fac Pharmaceut Sci, Toyama 9300194, Japan

来源：

CHEMICAL COMMUNICATIONS | 2005年 / 38期

关键词：

D O I：

10.1039/b508189k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A general and versatile molecular design for host molecules was proposed based on the structural motif of antibodies. A water-soluble potassium sensor was developed by this molecular design, which consists of three functional regions, benzo-15crown-5 ether, DNA, and pyrene as guest-binding, dimerising, and signaling sites, respectively. The molecular sensor emitted the monomer fluorescence of the pyrene fluorophore predominantly when existing as a random structure, while it formed a duplex upon recognition of K+ to bring about monomer-excimer emission switching.

引用

页码：4780 / 4782

页数：3

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