Azurin for biomolecular electronics: a reliability study

被引：5

作者：

Bramanti, A

Pompa, PP

Maruccio, G

Calabi, F

Arima, V

Cingolani, R

Corni, S

Di Felice, R

De Rienzo, F

Rinaldi, R

机构：

[1] Univ Lecce, NNL, INFM, I-73100 Lecce, Italy

[2] Univ Modena, Dipartimento Chim, I-41100 Modena, Italy

[3] Univ Modena, INFM S3, I-41100 Modena, Italy

来源：

JAPANESE JOURNAL OF APPLIED PHYSICS PART 1-REGULAR PAPERS BRIEF COMMUNICATIONS & REVIEW PAPERS | 2005年 / 44卷 / 9A期

关键词：

biomolecular electronics; protein devices; high electric fields; folding; device reliability; theoretical models; solid-state measurements;

D O I：

10.1143/JJAP.44.6864

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

The metalloprotein azurin, used in biomolecular electronics, is investigated with respect to its resilience to high electric fields and ambient conditions, which are crucial reliability issues. Concerning the effect of electric fields, two models of different complexity agree indicating an unexpectedly high robustness. Experiments in device-like conditions confirm that no structural modifications occur, according to fluorescence spectra, even after a 40-min exposure to tens of MV/m. Ageing is then investigated experimentally, at ambient conditions and without field, over several days. Only a small conformational rearrangement is observed in the first tens of hours, followed by an equilibrium state.

引用

页码：6864 / 6866

页数：3

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