Diacylglycerol - when is it an intracellular messenger?

被引：153

作者：

Wakelam, MJO ^{[1
]}

机构：

[1] Univ Birmingham, Queen Elizabeth Hosp, Inst Canc Studies, Birmingham B15 2TA, W Midlands, England

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS | 1998年 / 1436卷 / 1-2期

基金：

英国惠康基金;

关键词：

diacylglycerol; phosphatidate; protein kinase C; phospholipase C; phospholipase D;

D O I：

10.1016/S0005-2760(98)00123-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Distinct, structurally different forms of sn-1,2-diacylglycerol are found in cells, these are polyunsaturated, mono- or diunsaturated and saturated. The pathways that generate or metabolise sn-1,2-diacylglycerol are reviewed. The evidence that it is the polyunsaturated forms of sn-1,2-diacylglycerol,but the more saturated forms of phosphatidate which function as intracellular signals is considered. (C) 1998 Elsevier Science B.V. All rights reserved.

引用

页码：117 / 126

页数：10

共 98 条

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