Visual detection of cysteine and homocysteine

被引:483
作者
Rusin, O
St Luce, NN
Agbaria, RA
Escobedo, JO
Jiang, S
Warner, IM
Dawan, FB
Lian, K
Strongin, RM [1 ]
机构
[1] Louisiana State Univ, Dept Chem, Baton Rouge, LA 70803 USA
[2] Louisiana State Univ, Ctr Adv Microstruct & Devices, Baton Rouge, LA 70803 USA
关键词
D O I
10.1021/ja036297t
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The determination of cysteine and homocysteine levels is of great current interest for the monitoring of desease states. A new colorimetric method for the simultaneous detection of L-cysteine and L-homocysteine has been developed. A fluorescein derivative reacts with the above amino acids, producing their respective thiazolidines resulting in color changes. Interference from other amino acids and proteins is minimal. Copyright © 2004 American Chemical Society.
引用
收藏
页码:438 / 439
页数:2
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