Synthesis of ethyl 3-cyano-2-methylcinnamates and 3-cyano-2-methylcinnamonitriles from the Baylis-Hillman acetates

被引：79

作者：

Chung, YM

Gong, JH

Kim, TH

Kim, JN ^{[1
]}

机构：

[1] Chonnam Natl Univ, Dept Chem, Kwangju 500757, South Korea

[2] Chonnam Natl Univ, Inst Basic Sci, Kwangju 500757, South Korea

[3] Chonnam Natl Univ, Fac Appl Chem, Kwangju 500757, South Korea

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 51期

基金：

新加坡国家研究基金会;

关键词：

Baylis-Hillman acetates; ethyl; 3-cyano-2-methylcinnamates; DABCO;

D O I：

10.1016/S0040-4039(01)01971-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of the DABCO salts 2, generated in situ from the Baylis-Hillman acetates 1, and KCN in aqueous THF gave ethyl 3-cyano-2-methylcinnamates 4a-d and 3-cyano-2-methylcinnamonitriles 4e-f in good yields. (C) 2001 Elsevier Science Ltd. All rights reserved.

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收藏

页码：9023 / 9026

页数：4

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