Modulation of methylation in the FMR1 promoter region after long term treatment with L-carnitine and acetyl-L-carnitine -: art. no. e76

被引：11

作者：

Pascale, E

Battiloro, E

Reale, GC

Pietrobono, R

Pomponi, MG

Chiurazzi, P

Nicolai, R

Calvani, M

Neri, G

D'Ambrosio, E

机构：

[1] CNR, Ist Neurobiol & Med Mol, I-00137 Rome, Italy

[2] Univ Roma La Sapienza, Dipartimento Med Mol & Patol, Rome, Italy

[3] Univ Cattolica, Ist Genet Med, Rome, Italy

[4] Policlin Univ, Dipartimento Pediat, Messina, Italy

来源：

JOURNAL OF MEDICAL GENETICS | 2003年 / 40卷 / 06期

关键词：

D O I：

10.1136/jmg.40.6.e76

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

引用

页数：5

共 28 条

[1] Histone modifications in transcriptional regulation [J].

Berger, SL .

CURRENT OPINION IN GENETICS & DEVELOPMENT, 2002, 12 (02) :142-148

[2] Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer [J].

Cameron, EE ;

Bachman, KE ;

Myöhänen, S ;

Herman, JG ;

Baylin, SB .

NATURE GENETICS, 1999, 21 (01) :103-107

[3] Synergistic effect of histone hyperacetylation and DNA demethylation in the reactivation of the FMR1 gene [J].

Chiurazzi, P ;

Pomponi, MG ;

Pietrobono, R ;

Bakker, CE ;

Neri, G ;

Oostra, BA .

HUMAN MOLECULAR GENETICS, 1999, 8 (12) :2317-2323

[4] In vitro reactivation of the FMR1 gene involved in fragile X syndrome [J].

Chiurazzi, P ;

Pomponi, MG ;

Willemsen, R ;

Oostra, BA ;

Neri, G .

HUMAN MOLECULAR GENETICS, 1998, 7 (01) :109-113

[5]

CLARK SJ, 1994, NUCLEIC ACIDS RES, V22, P2990, DOI 10.1093/nar/22.15.2990

[6] Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells [J].

Coffee, B ;

Zhang, FP ;

Warren, ST ;

Reines, D .

NATURE GENETICS, 1999, 22 (01) :98-101

[7] Variable FMR1 gene methylation of large expansions leads to variable phenotype in three males from one fragile X family [J].

deVries, BBA ;

Jansen, CCAM ;

Duits, AA ;

Verheij, C ;

Willemsen, R ;

vanHemel, JO ;

vandenOuweland, AMW ;

Niermeijer, MF ;

Oostra, BA ;

Halley, DJJ .

JOURNAL OF MEDICAL GENETICS, 1996, 33 (12) :1007-1010

[8] CARNITINE SUPPRESSION OF POSITION EFFECT VARIEGATION IN DROSOPHILA-MELANOGASTER [J].

FANTI, L ;

BERLOCO, M ;

PIMPINELLI, S .

MOLECULAR AND GENERAL GENETICS, 1994, 244 (06) :588-595

[9]

Glenn CC, 1996, AM J HUM GENET, V58, P335

[10] HIGH FUNCTIONING FRAGILE-X MALES - DEMONSTRATION OF AN UNMETHYLATED FULLY EXPANDED FMR-1 MUTATION ASSOCIATED WITH PROTEIN EXPRESSION [J].

HAGERMAN, RJ ;

HULL, CE ;

SAFANDA, JF ;

CARPENTER, I ;

STALEY, LW ;

OCONNOR, RA ;

SEYDEL, C ;

MAZZOCCO, MMM ;

SNOW, K ;

THIBODEAU, SN ;

KUHL, D ;

NELSON, DL ;

CASKEY, CT ;

TAYLOR, AK .

AMERICAN JOURNAL OF MEDICAL GENETICS, 1994, 51 (04) :298-308

← 1 2 3 →