Circumdatin G, a new alkaloid from the fungus Aspergillus ochraceus

被引：106

作者：

Dai, JR

Carté, BK

Sidebottom, PJ

Yew, ALS

Ng, SB

Huang, YC

Butler, MS

机构：

[1] Ctr Nat Prod Res, Inst Mol & Cell Biol, Singapore 118240, Singapore

[2] Glaxo Wellcome Res & Dev Ltd, Stevenage SG1 2NY, Herts, England

来源：

JOURNAL OF NATURAL PRODUCTS | 2001年 / 64卷 / 01期

关键词：

D O I：

10.1021/np000381u

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The crude extract of the broth of Aspergillus ochraceus was found to inhibit the final stage of polyprotein processing during hepatitis C virus replication. Bioassay-guided fractionation led to the isolation of the known compound mellein as the active component of the extract. Also isolated were circumdatin F and a new alkaloid, circumdatin G. The structure of circumdatin G was determined by spectroscopic analysis.

引用

页码：125 / 126

页数：2