The evolving relationship between Chlamydia pneumoniae and atherosclerosis

被引：4

作者：

Dunne, M ^{[1
]}

机构：

[1] Pfizer Global Res Div, Groton, CT 06340 USA

来源：

CURRENT OPINION IN INFECTIOUS DISEASES | 2000年 / 13卷 / 06期

关键词：

D O I：

10.1097/00001432-200012000-00002

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

A body of evidence supports an association between Chlamydia pneumoniae and atherosclerosis. Recent prospective, seroepidemiologic studies have refined estimations of relative risk. Advances in diagnostic testing with the polymerase chain reaction have created a potential opportunity to screen for infected individuals. New insights into the pathogenesis of infection with C. pneumoniae have been reported, many of which are relevant to the development of atherosclerotic plaque. Clinical trials have now been initiated and should provide guidance as to the utility of antibiotics in the treatment or prevention of coronary artery disease. Curr Opin Infect Dis 13:583-591. (C) 2000 Lippincott Williams & Wilkins.

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页码：583 / 591

页数：9

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