anti-sulfonamide antibodies catalyse the hydrolysis of a heterocyclic amide

被引:14
作者
Benedetti, F
Berti, F
Colombatti, A
Ebert, C
Linda, P
Tonizzo, F
机构
[1] UNIV UDINE,DIPARTIMENTO SCI & TECNOL BIOMED,I-33100 UDINE,ITALY
[2] UNIV TRIESTE,DIPARTIMENTO SCI FARMACEUT,I-34127 TRIESTE,ITALY
关键词
D O I
10.1039/cc9960001417
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The hydrolysis of N-p-toluoylindole and its 3-formyl derivative, at pH 8.0, are accelerated by a factor of nearly 10(3) by an antibody obtained against a KLH conjugate of N-p-toluensulfonylindole.
引用
收藏
页码:1417 / 1418
页数:2
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