Prevalence and abundance of uncultivated Megasphaera-like bacteria in the human vaginal environment

被引:36
作者
Zozaya-Hinchliffe, Marcela [1 ]
Martin, David H. [2 ,3 ]
Ferris, Michael J. [1 ]
机构
[1] Res Inst Childrens, New Orleans, LA USA
[2] Louisiana State Univ, Dept Pediat, New Orleans, LA USA
[3] Louisiana State Univ, Dept Internal Med, New Orleans, LA USA
关键词
D O I
10.1128/AEM.02127-07
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Cultivation-independent analysis of 16S rRNA gene sequences in vaginal samples revealed two previously unrecognized, uncultivated Megasphaera-like phylotypes. Phylogenetic analysis and environmental distribution suggest that these Megasphaera types may be unique to the vaginal environment. Quantitative PCR suggests that both phylotypes are present in higher concentrations in women with bacterial vaginosis.
引用
收藏
页码:1656 / 1659
页数:4
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