Conversion of aldehydes to amides via dimethyl sulfoxide oxidation of the corresponding α-aminonitriles

被引：17

作者：

Enders, D ^{[1
]}

Amaya, AS ^{[1
]}

Pierre, F ^{[1
]}

机构：

[1] Rhein Westfal TH Klinikum, Inst Organ Chem, D-52074 Aachen, Germany

来源：

NEW JOURNAL OF CHEMISTRY | 1999年 / 23卷 / 03期

关键词：

D O I：

10.1039/a809770d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Unsaturated, aryl and heteroaryl N-dialkyl-alpha-aminonitriles are easily oxidized at room temperature to their corresponding tertiary N-dialkylamides by using dimethyl sulfoxide and bases like (BuOK)-O-t or KOH, The reaction offers an efficient two-step conversion of aldehydes to N-dialkyamides.

引用

页码：261 / 262

页数：2

共 17 条

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