Single-clamp technique does not protect against cerebrovascular accident in coronary artery bypass grafting

被引:17
作者
Kim, RW
Mariconda, DC
Tellides, G
Kopf, GS
Dewar, ML
Lin, ZQ
Elefteriades, JA
机构
[1] Yale Univ, Sch Med, Dept Surg, Sect Cardiothorac Surg, New Haven, CT 06510 USA
[2] Yale Univ, Sch Med, Sect Cardiothorac Surg, Dept Surg, New Haven, CT 06510 USA
[3] Yale New Haven Hosp, Ctr Outcomes Res, New Haven, CT 06510 USA
关键词
coronary disease; surgery; stroke; complications;
D O I
10.1016/S1010-7940(01)00765-5
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives: By potentially avoiding the embolic consequences of a side-biting aortic clamp, the single-clamp technique may decrease cerebrovascular accidents in coronary artery bypass grafting. However, this theoretical superiority in stroke prevention has not been conclusively demonstrated and use of this technique may lead to adverse myocardial effects due to longer cross-clamp times. In this study, we sought to determine if the single-clamp technique prevents postoperative stroke in clinical practice. Methods: Of 607 consecutive isolated coronary bypass operations completed over a 3 year period, 301 (50%) were performed by one surgeon using exclusively the single-clamp technique and 306 (50%) were performed by a second surgeon using exclusively the two-clamp technique. Postoperative adverse events were retrospectively compared between these two groups. Results: There were no differences between groups in terms of postoperative stroke (1.7% single-clamp vs. 2.0% two-clamp, P = 0.78), hospital mortality (2.7% single-clamp vs. 1.6% two-clamp, P = 0.38), or perioperative myocardial infarction (2.6% single-clamp vs. 0.7% two-clamp, P = 0.052). The two-clamp technique was not a significant predictor of stroke by logistic regression analysis (P = 0.72). Conclusions: We conclude that there are no statistically significant differences between clamp techniques with regard to stroke prevention or myocardial protection. We find no compelling evidence for surgeons successfully utilizing one technique to change to the other. (C) 2001 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:127 / 132
页数:6
相关论文
共 20 条
[11]   Risk factors and solutions for the development of neurobehavioral changes after coronary artery bypass grafting [J].
Hammon, JW ;
Stump, DA ;
Kon, ND ;
Cordell, AR ;
Hudspeth, AS ;
Oaks, TE ;
Brooker, RF ;
Rogers, AT ;
Hilbawi, R ;
Coker, LH ;
Troost, BT .
ANNALS OF THORACIC SURGERY, 1997, 63 (06) :1613-1618
[12]   MANAGEMENT OF THE SEVERELY ATHEROSCLEROTIC AORTA DURING CARDIAC OPERATIONS [J].
KOUCHOUKOS, NT ;
WAREING, TH ;
DAILY, BB ;
MURPHY, SF .
JOURNAL OF CARDIAC SURGERY, 1994, 9 (05) :490-494
[13]  
LOOP FD, 1992, J THORAC CARDIOV SUR, V104, P608
[14]  
MILLS NL, 1991, J THORAC CARDIOV SUR, V102, P546
[15]   Prospective randomized trial of single clamp technique versus intermittent ischaemic arrest: myocardial and neurological outcome [J].
Musumeci, F ;
Feccia, M ;
MacCarthy, PA ;
Ellis, GR ;
Mammana, L ;
Brinn, F ;
Penny, WJ .
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 1998, 13 (06) :702-709
[16]  
RAJALIN A, 1995, SCAND J THORAC CARD, V29, P174
[17]  
REICHENSPURNER H, 1999, NEUROL INQUIRY CARDI, V3, P46
[19]  
Stefaniszyn H J, 1984, Curr Surg, V41, P184
[20]  
YAMAGUCHI A, 1993, J JPN ASS THOR SURG, V41, P1194