The first electrochemical study of epidithiopiperazine-2,5-diones, a special class of α,α′-disulfide bridged cyclic dipeptides

被引：12

作者：

Chai, CLL ^{[1
]}

Heath, GA

Huleatt, PB

O'Shea, GA

机构：

[1] Australian Natl Univ, The Faculties, Dept Chem, Canberra, ACT 0200, Australia

[2] Australian Natl Univ, Inst Adv Studies, Res Sch Chem, Canberra, ACT 0200, Australia

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2 | 1999年 / 03期

关键词：

D O I：

10.1039/a809266d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Polarographic studies of 3,6-epidithiopiperazine-2,5-diones (ETP) including naturally occurring gliotoxin and simple synthetic analogues are pertinent to understanding their biological action; coulometric measurements on 1,4-diethyl ETP in acetonitrile establish the existence of a ready one-electron reduction overall, in sharp contrast to the familiar two-electron cleavage of acyclic disulfides.

引用

页码：389 / 391

页数：3

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