Early effects of C-60 administration in Swiss mice: A preliminary account for in vivo C-60 toxicity.

被引：62

作者：

Moussa, F

Trivin, F

Ceolin, R

Hadchouel, M

Sizaret, PY

Greugny, V

Fabre, C

Rassat, A

Szwarc, H

机构：

[1] FAC PHARM REIMS,SERV MICROSCOPIE ELECTR,F-37200 TOURS,FRANCE

[2] FAC MED,F-37200 TOURS,FRANCE

[3] HOP BICETRE,INSERM U347,F-94276 LE KREMLIN BICETR,FRANCE

[4] ECOLE NORMALE SUPER,CHIM LAB,URA 1679 CNRS,F-75231 PARIS,FRANCE

[5] UNIV PARIS 11,LAB CHIM PHYS MAT AMORPHES,URA D 1104 CNRS,F-91405 ORSAY,FRANCE

来源：

FULLERENE SCIENCE AND TECHNOLOGY | 1996年 / 4卷 / 01期

关键词：

D O I：

10.1080/10641229608001534

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

High amounts of micronized C-60 have been injected intraperitoneally into Swiss mice. Until the fourteenth day, they were still alive without any behaviour trouble. C-60 was well absorbed, and found localized in spleen and liver. Inside the liver, C-60 was detected in Kupffer cells and hepatocytes. But the main result is the induced hypertrophy of the perisinusoidal cells, where C-60 preferentially accumulates.

引用

页码：21 / 29

页数：9

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