Accurate diagnosis of Helicobacter pylori -: Polymerase chain reaction tests

被引：23

作者：

Ho, GY ^{[1
]}

Windsor, HM ^{[1
]}

机构：

[1] Univ Western Australia, Dept Microbiol, NHMRC Helicobacter Pylori Res Lab, Perth, WA 6009, Australia

来源：

GASTROENTEROLOGY CLINICS OF NORTH AMERICA | 2000年 / 29卷 / 04期

关键词：

D O I：

10.1016/S0889-8553(05)70158-8

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Polymerase chain reaction (PCR) can be used for the detection of Helicobacter pylori in gastric tissue samples. PCR provides a rapid, sensitive and specific test result and is particularly useful for a gastroenterologist who does not have access to local routine laboratory facilities. As the H. pylori organisms are not required to be alive when tested, there are no special requirements in the handling, transport and storage of the gastric biopsies. In addition, PCR has the potential for determining antibiotic sensitivity and pathogenicity of the infecting H. pylori strain and also for epidemiologic and retrospective studies.

引用

收藏

页码：903 / +

页数：14

相关论文

共 81 条

[1]

Akashi H, 1996, J GASTROENTEROL, V31, P16

[2] Detection of Helicobacter pylori in gastric biopsy and resection specimens [J].

AshtonKey, M ;

Diss, TC ;

Isaacson, PG .

JOURNAL OF CLINICAL PATHOLOGY, 1996, 49 (02) :107-111

[3] MOSAICISM IN VACUOLATING CYTOTOXIN ALLELES OF HELICOBACTER-PYLORI - ASSOCIATION OF SPECIFIC VACA TYPES WITH CYTOTOXIN PRODUCTION AND PEPTIC-ULCERATION [J].

ATHERTON, JC ;

CAO, P ;

PEEK, RM ;

TUMMURU, MKR ;

BLASER, MJ ;

COVER, TL .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (30) :17771-17777

[4]

Basso D, 1996, Helicobacter, V1, P159, DOI 10.1111/j.1523-5378.1996.tb00031.x

[5] Fecal PCR assay for diagnosis of Helicobacter infection in laboratory rodents [J].

Beckwith, CS ;

Franklin, CL ;

Hook, RR ;

BeschWilliford, CL ;

Riley, LK .

JOURNAL OF CLINICAL MICROBIOLOGY, 1997, 35 (06) :1620-1623

[6]

Björkholm B, 1998, J CLIN MICROBIOL, V36, P3689

[7] Isolation of a genetic locus associated with metronidazole resistance in Helicobacter pylori [J].

Chang, KC ;

Ho, SW ;

Yang, JC ;

Wang, JT .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1997, 236 (03) :785-788

[8] SENSITIVE DETECTION OF HELICOBACTER-PYLORI BY USING POLYMERASE CHAIN-REACTION [J].

CLAYTON, CL ;

KLEANTHOUS, H ;

COATES, PJ ;

MORGAN, DD ;

TABAQCHALI, S .

JOURNAL OF CLINICAL MICROBIOLOGY, 1992, 30 (01) :192-200

[9] MOLECULAR CHARACTERIZATION OF THE 128-KDA IMMUNODOMINANT ANTIGEN OF HELICOBACTER-PYLORI-ASSOCIATED WITH CYTOTOXICITY AND DUODENAL-ULCER [J].

COVACCI, A ;

CENSINI, S ;

BUGNOLI, M ;

PETRACCA, R ;

BURRONI, D ;

MACCHIA, G ;

MASSONE, A ;

PAPINI, E ;

XIANG, ZY ;

FIGURA, N ;

RAPPUOLI, R .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (12) :5791-5795

[10]

DebetsOssenkopp YJ, 1996, FEMS MICROBIOL LETT, V142, P37, DOI 10.1016/0378-1097(96)00239-X

← 1 2 3 4 5 6 7 8 9 →