Electrical power fuels rotary ATP synthase

被引:41
作者
Dimroth, P [1 ]
von Ballmoos, C [1 ]
Meier, T [1 ]
Kaim, G [1 ]
机构
[1] ETH Zentrum, Inst Mikrobiol Eidgenossischen Tech Hsch, CH-8092 Zurich, Switzerland
关键词
D O I
10.1016/j.str.2003.11.011
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
ATP synthesis by F-type ATP synthases consumes energy stored in a transmembrane electrochemical gradient of protons or sodium ions. The electric component of the ion motive force is crucial for ATP synthesis. Here, we incorporate recent results on structure and function of the F-0 domain and present a mechanism for torque generation with the fundamental nature of the membrane potential as driving force in the core.
引用
收藏
页码:1469 / 1473
页数:5
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