Debromination of 8-bromo-2′-deoxyguanosine by methylene blue and visible light

被引：5

作者：

Venkatarangan, L ^{[1
]}

Yang, DH ^{[1
]}

Epling, GA ^{[1
]}

Basu, AK ^{[1
]}

机构：

[1] Univ Connecticut, Dept Chem, Storrs, CT 06269 USA

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 08期

关键词：

electron transfer; photolysis; dehalogenation; nucleoside;

D O I：

10.1016/S0040-4039(99)00005-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Debromination of 8-bromo-2'-deoxyguanosine was accomplished in high yield under neutral conditions in aqueous methanol by irradiating with visible light in the presence of methylene blue as a sensitizer and triethylamine as an electron donor. The method can be extended for the debromination of other bromoaromatic compounds. (C) 1999 Elsevier Science Ltd. Ail rights reserved.

引用

页码：1441 / 1444

页数：4