A selenolactone-based fluorescent chemodosimeter to monitor mecury/methylmercury species in vitro and in vivo

被引:122
作者
Chen, Xiaoqiang [1 ,4 ]
Baek, Kyung-Hwa [2 ]
Kim, Youngmee [1 ]
Kim, Sung-Jin [1 ]
Shin, Injae [2 ]
Yoon, Juyoung [1 ,3 ]
机构
[1] Ewha Womans Univ, Dept Chem & Nano Sci, Seoul 120750, South Korea
[2] Yonsei Univ, Dept Chem, Ctr Biofunct Mol, Seoul 120749, South Korea
[3] Ewha Womans Univ, Dept Bioinspired Sci, Seoul 120750, South Korea
[4] Nanjing Univ Technol, Coll Chem & Chem Engn, State Key Lab Mat Oriented Chem Engn, Nanjing 210009, Peoples R China
基金
新加坡国家研究基金会;
关键词
Fluorescent chemodosimeter; Selenolactone; Rhodamine; Mecury; Methylmercury; SELECTIVE FLUORESCENT; RECOGNITION PREFERENCE; HG2+ IONS; MERCURY; CHEMOSENSORS; HG(II); DERIVATIVES; METHYLMERCURY; PROBE; METHYLATION;
D O I
10.1016/j.tet.2010.04.042
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A fluorescent probe based on selenolactone displays unique fluorescence enhancement and UV vis spectral change for mercury/methylmercury species, which were attributed to deselenation reaction. The value of this system was successfully demonstrated by its use in detecting inorganic mercury/methylmercury species in cells and zebrafish. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码:4016 / 4021
页数:6
相关论文
共 52 条
[1]  
[Anonymous], 1999, ATSDR TOX PROF MERC
[2]   Luminescent sensors and switches in the early 21st century [J].
Callan, JF ;
de Silva, AP ;
Magri, DC .
TETRAHEDRON, 2005, 61 (36) :8551-8588
[3]   Abiotic methylation of mercury in the aquatic environment [J].
Celo, Valbona ;
Lean, David R. S. ;
Scott, Susannah L. .
SCIENCE OF THE TOTAL ENVIRONMENT, 2006, 368 (01) :126-137
[4]   Hg2+ Selective Fluorescent and Colorimetric Sensor: Its Crystal Structure and Application to Bioimaging [J].
Chen, Xiaoqiang ;
Nam, Seong-Won ;
Jou, Min Jung ;
Kim, Youngmee ;
Kim, Sung-Jin ;
Park, Sungsu ;
Yoon, Juyoung .
ORGANIC LETTERS, 2008, 10 (22) :5235-5238
[5]   A thiol-specific fluorescent probe and its application for bioimaging [J].
Chen, Xiaoqiang ;
Ko, Sung-Kyun ;
Kim, Min Jung ;
Shin, Injae ;
Yoon, Juyoung .
CHEMICAL COMMUNICATIONS, 2010, 46 (16) :2751-2753
[6]   Thin-Film Formation of Imidazolium-Based Conjugated Polydiacetylenes and Their Application for Sensing Anionic Surfactants [J].
Chen, Xiaoqiang ;
Kang, Sunwoo ;
Kim, Min Jung ;
Kim, Joohee ;
Kim, Youn Sang ;
Kim, Heejin ;
Chi, Bo ;
Kim, Sung-Jin ;
Lee, Jin Yong ;
Yoon, Juyoung .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (08) :1422-1425
[7]   Hg2+-selective chromogenic and fluorogenic chemodosimeter based on thiocoumarins [J].
Choi, Myung Gil ;
Kim, Youn Hwan ;
Namgoong, Ji Eun ;
Chang, Suk-Kyu .
CHEMICAL COMMUNICATIONS, 2009, (24) :3560-3562
[8]   The toxicology of mercury - Current exposures and clinical manifestations [J].
Clarkson, TW ;
Magos, L ;
Myers, GJ .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 349 (18) :1731-1737
[9]   Signal ratio amplification via modulation of resonance energy transfer: Proof of principle in an emission ratiometric Hg(II) sensor [J].
Coskun, Ali ;
Akkaya, Engin U. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (45) :14474-14475
[10]   CHEMICAL COMMUNICATION IN WATER USING FLUORESCENT CHEMOSENSORS [J].
CZARNIK, AW .
ACCOUNTS OF CHEMICAL RESEARCH, 1994, 27 (10) :302-308