Antibody libraries in drug and target discovery

被引：24

作者：

Rader, C ^{[1
]}

机构：

[1] Scripps Res Inst, Dept Mol Biol, La Jolla, CA 92037 USA

来源：

DRUG DISCOVERY TODAY | 2001年 / 6卷 / 01期

关键词：

D O I：

10.1016/S1359-6446(00)01595-6

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Antibody libraries have come of age in the generation and evolution of monoclonal antibodies for therapeutic applications. Here, with an emphasis on cancer therapy, several examples are presented that illustrate the ability to design, engineer and select antibody libraries for different rationales in drug and target discovery.

引用

页码：36 / 43

页数：8

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