The Universal Protein Resource (UniProt)

被引:543
作者
Bairoch, Amos [3 ,4 ]
Bougueleret, Lydie [3 ,4 ]
Altairac, Severine [3 ,4 ]
Amendolia, Valeria [3 ,4 ]
Auchincloss, Andrea [3 ,4 ]
Puy, Ghislaine Argoud [3 ,4 ]
Axelsen, Kristian [3 ,4 ]
Baratin, Delphine [3 ,4 ]
Blatter, Marie-Claude [3 ,4 ]
Boeckmann, Brigitte [3 ,4 ]
Bollondi, Laurent [3 ,4 ]
Boutet, Emmanuel [3 ,4 ]
Quintaje, Silvia Braconi [3 ,4 ]
Breuza, Lionel [3 ,4 ]
Bridge, Alan [3 ,4 ]
Saux, Virginie Bulliard-Le [3 ,4 ]
decastro, Edouard [3 ,4 ]
Ciampina, Luciane [3 ,4 ]
Coral, Danielle [3 ,4 ]
Coudert, Elisabeth [3 ,4 ]
Cusin, Isabelle [3 ,4 ]
David, Fabrice [3 ,4 ]
Delbard, Gwennaelle [3 ,4 ]
Dornevil, Dolnide [3 ,4 ]
Duek-Roggli, Paula [3 ,4 ]
Duvaud, Severine [3 ,4 ]
Estreicher, Anne [3 ,4 ]
Famiglietti, Livia [3 ,4 ]
Farriol-Mathis, Nathalie [3 ,4 ]
Ferro, Serenella [3 ,4 ]
Feuermann, Marc [3 ,4 ]
Gasteiger, Elisabeth [3 ,4 ]
Gateau, Alain [3 ,4 ]
Gehant, Sebastian [3 ,4 ]
Gerritsen, Vivienne [3 ,4 ]
Gos, Arnaud [3 ,4 ]
Gruaz-Gumowski, Nadine [3 ,4 ]
Hinz, Ursula [3 ,4 ]
Hulo, Chantal [3 ,4 ]
Hulo, Nicolas [3 ,4 ]
Innocenti, Alessandro [3 ,4 ]
James, Janet [3 ,4 ]
Jain, Eric [3 ,4 ]
Jimenez, Silvia [3 ,4 ]
Jungo, Florence [3 ,4 ]
Junker, Vivien [3 ,4 ]
Keller, Guillaume [3 ,4 ]
Lachaize, Corinne [3 ,4 ]
Lane-Guermonprez, Lydie [3 ,4 ]
Langendijk-Genevaux, Petra [3 ,4 ]
机构
[1] European Bioinformat Inst, EMBL Outstn, Hinxton CB10 1SD, Cambs, England
[2] Georgetown Univ, Med Ctr, Protein Informat Resource, Washington, DC 20007 USA
[3] Univ Geneva, Swiss Inst Bioinformat, CH-1211 Geneva 4, Switzerland
[4] Univ Geneva, Dept Med Biochem, CH-1211 Geneva 4, Switzerland
关键词
D O I
10.1093/nar/gkm895
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The Universal Protein Resource (UniProt) provides a stable, comprehensive, freely accessible, central resource on protein sequences and functional annotation. The UniProt Consortium is a collaboration between the European Bioinformatics Institute (EBI), the Protein Information Resource (PIR) and the Swiss Institute of Bioinformatics (SIB). The core activities include manual curation of protein sequences assisted by computational analysis, sequence archiving, development of a user-friendly UniProt website, and the provision of additional value-added information through cross-references to other databases. UniProt is comprised of four major components, each optimized for different uses: the UniProt Knowledgebase, the UniProt Reference Clusters, the UniProt Archive and the UniProt Metagenomic and Environmental Sequences database. UniProt is updated and distributed every three weeks, and can be accessed online for searches or download at http://www.uniprot.org.
引用
收藏
页码:D190 / D195
页数:6
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