CompariMotif: quick and easy comparisons of sequence motifs

被引:40
作者
Edwards, Richard J. [1 ,2 ,3 ]
Davey, Norman E. [1 ,2 ]
Shields, Denis C. [1 ,2 ]
机构
[1] Univ Coll Dublin, UCD Complex & Adapt Syst Lab, Dublin 4, Ireland
[2] Univ Coll Dublin, UCD Conway Inst Biomol & Biomed Sci, Dublin 4, Ireland
[3] Univ Southampton, Sch Biol Sci, Southampton SO16 7PX, Hants, England
基金
爱尔兰科学基金会;
关键词
D O I
10.1093/bioinformatics/btn105
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
CompariMotif is a novel tool for making motifmotif comparisons, identifying and describing similarities between regular expression motifs. CompariMotif can identify a number of different relationships between motifs, including exact matches, variants of degenerate motifs and complex overlapping motifs. Motif relationships are scored using shared information content, allowing the best matches to be easily identified in large comparisons. Many input and search options are available, enabling a list of motifs to be compared to itself (to identify recurring motifs) or to datasets of known motifs.
引用
收藏
页码:1307 / 1309
页数:3
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