β-Lactoglobulin as source of bioactive peptides

被引:162
作者
Hernandez-Ledesma, B. [1 ]
Recio, I. [1 ]
Amigo, L. [1 ]
机构
[1] CSIC, Inst Fermentac Ind, E-28006 Madrid, Spain
关键词
beta-Lactoglobulin; bioactive peptides; physiological activity;
D O I
10.1007/s00726-007-0585-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
beta-Lactoglobulin (beta-Lg) is currently an important source of biologically active peptides. These peptides are inactive within the sequence of the precursor protein, but they can be released by in vivo or in vitro enzymatic proteolysis. Once released, these peptides play important roles in the human health, including antihypertensive, antioxidant and antimicrobial activities as well as opioid-like features and ability to decrease the body-cholesterol levels. Bioactive peptides derived from beta-Lg are currently a point of intensive research. Their structure, biological significance and mechanism of action are briefly presented and discussed in this review.
引用
收藏
页码:257 / 265
页数:9
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