Antiphospholipid syndrome: Review

被引：14

作者：

Sammaritano, LR ^{[1
]}

机构：

[1] Cornell Univ, Weill Med Coll, Hosp Special Surg, New York, NY 10021 USA

来源：

SOUTHERN MEDICAL JOURNAL | 2005年 / 98卷 / 06期

关键词：

acquired thrombophilia; anticardiolipin antibody; antiphospholipid syndrome; lupus anticoagulant; recurrent pregnancy loss; thrombosis;

D O I：

10.1097/01.smj.0000166748.90089.65

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Antiphospholipid syndrome spans many medical disciplines. Classic criteria include the presence of anticardiolipin antibody or lupus anticoagulant with typical complications of thrombosis or pregnancy loss. Other common associated manifestations include livedo reticularis, thrombocytopenia, valvular heart disease, and nephropathy with renal insufficiency, hypertension, and proteinuria. Treatment of serious complications with anticoagulation is standard; generally warfarin for thrombosis and aspirin/heparin for pregnancy prophylaxis. Detailed recommendations regarding precise intensity and duration of anticoagulation are still a subject of debate.

引用

页码：617 / 625

页数：9

共 75 条

[31] Antiphospholipid antibodies induced in mice by immunization with a cytomegalovirus-derived peptide cause thrombosis and activation of endothelial cells in vivo [J].

Gharavi, AE ;

Pierangeli, SS ;

Espinola, RG ;

Liu, XW ;

Colden-Stanfield, M ;

Harris, EN .

ARTHRITIS AND RHEUMATISM, 2002, 46 (02) :545-552

[32] Antiphospholipid syndrome and the skin [J].

Gibson, GE ;

Su, WPD ;

Pittelkow, MR .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1997, 36 (06) :970-982

[33] ANTICARDIOLIPIN ANTIBODIES AND THE RISK FOR ISCHEMIC STROKE AND VENOUS THROMBOSIS [J].

GINSBURG, KS ;

LIANG, MH ;

NEWCOMER, L ;

GOLDHABER, SZ ;

SCHUR, PH ;

HENNEKENS, CH ;

STAMPFER, MJ .

ANNALS OF INTERNAL MEDICINE, 1992, 117 (12) :997-1002

[34]

Godfrey T, 2000, HUGHES SYNDROME: ANTIPHOSPHOLIPID SYNDROME, P8

[35]

Gris JC, 1999, THROMB HAEMOSTASIS, V81, P891

[36]

HARRIS EN, 1991, AM J OBSTET GYNECOL, V165, P1272

[37] Atherosclerosis and antiphospholipid syndrome [J].

Jara, LJ ;

Medina, G ;

Vera-Lastra, O ;

Shoenfeld, Y .

CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY, 2003, 25 (01) :79-87

[38] INTRAVENOUS IMMUNOGLOBULIN TREATMENT OF PREGNANT PATIENTS WITH RECURRENT PREGNANCY LOSSES ASSOCIATED WITH ANTIPHOSPHOLIPID ANTIBODIES [J].

KAAJA, R ;

JULKUNEN, H ;

AMMALA, P ;

PALOSUO, T ;

KURKI, P .

ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, 1993, 72 (01) :63-66

[39] THE MANAGEMENT OF THROMBOSIS IN THE ANTIPHOSPHOLIPID-ANTIBODY SYNDROME [J].

KHAMASHTA, MA ;

CUADRADO, MJ ;

MUJIC, F ;

TAUB, NA ;

HUNT, BJ ;

HUGHES, GRV .

NEW ENGLAND JOURNAL OF MEDICINE, 1995, 332 (15) :993-997

[40]

Kutteh WH, 1996, AM J REPROD IMMUNOL, V35, P402

← 1 2 3 4 5 6 7 8 →